Serine,N-[(1,1-dimethylethoxy)carbonyl]-

Serine,N-[(1,1-dimethylethoxy)carbonyl]- - Names and Identifiers

Name	Serine,N-[(1,1-dimethylethoxy)carbonyl]-
Synonyms	Boc-DL-serine (tert-Butoxycarbonyl)serine (Tert-Butoxy)Carbonyl DL-Ser-OH Serine,N-[(1,1-diMethylethoxy)carbonyl]- Serine,N-[(1,1-dimethylethoxy)carbonyl]- DL-Serine,N-[(1,1-dimethylethoxy)carbonyl]- Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI) Serine, N-carboxy-, N-tert-butyl ester, DL-(8CI) 3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
CAS	3850-40-6

Serine,N-[(1,1-dimethylethoxy)carbonyl]- - Physico-chemical Properties

Molecular Formula	C8H15NO5
Molar Mass	205.21
Density	1.240±0.06 g/cm3(Predicted)
Boling Point	385.1±37.0 °C(Predicted)
pKa	3.62±0.10(Predicted)
Storage Condition	2-8°C

Serine,N-[(1,1-dimethylethoxy)carbonyl]- - Introduction

Serine,N-[(1,1-dimethylethoxy)carbonyl]-is a chemical reagent whose chemical name is serine, N-[(1,1-dimethylethoxy)carbonyl]-. This compound is obtained by introducing a protecting group (Boc group) on serine.
The properties of Serine,N-[(1,1-dimenthylethoxy) carbonyl]-mainly include:
-Appearance: White crystalline solid
-Molecular formula: C11H21NO5
-Molecular weight: 243.29g/mol
-Melting Point: 78-80°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and chloroform

Serine,N-[(1,1-dimenthylethoxy) carbonyl]-Mainly used in the field of organic synthesis as an intermediate for the synthesis of polypeptides. It can be used as a protecting group for serine to prevent it from side reactions in the reaction. In polypeptide synthesis, it can restore the activity of serine by removing the protecting group.

Serine,N-[(1,1-dimenthylethoxy) carbonyl]-is generally prepared by the following steps:
1. serine reacts with a protecting reagent of Boc group to generate Serine,N-[(1,1-dimenthylethoxy) carbonyl]-under alkaline conditions-.
2. The product was crystallized and purified to obtain the desired product.

Regarding safety information, Serine,N-[(1,1-dimenthylethoxy) carbonyl]-is a chemical reagent that needs to be handled with care. Observe the following safety measures:
-Use appropriate personal protective equipment during operation, such as laboratory gloves and safety glasses.
-Avoid contact with skin and inhalation of powder or gas.
-Read and understand the relevant Chemical Safety Data Sheet (SDS) before use.
-Store in a dry, cool place away from fire and oxidizing agents.

It should be noted that for the use and handling of chemical reagents, it is very important to strictly comply with laboratory safety procedures and local regulations.

Last Update：2024-04-10 22:29:15